Sermorelin | GRF 1-29 modified (CJC 1295 w/o DAC) | CJC 1295 w/ DAC
Stimulates pituitary to produce and release GH
Action of GHRH counteracted by somatostatin (prevents GH release)
GHRH increases levels of GH and IGF-1. They act back on hypothalamus to stimulate somatostatin for balance hormone production.
GHRHs ARE PLEOTROPIC
Have direct effect on cells
Effects are systemic
Signifciant down regulation of inflammatory response
Assist in wound healing
Immune sustem function
Involved in glucose homeostasis
IGF-1 initiates intracellular signaling. Influences everything: bone, cartilage, muscle, nerves, liver, lungs, and skin.